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iv solvent hazard scoring per gsk or pfizer solvent guides  (Pfizer Inc)

 
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    Pfizer Inc iv solvent hazard scoring per gsk or pfizer solvent guides
    Iv Solvent Hazard Scoring Per Gsk Or Pfizer Solvent Guides, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/iv solvent hazard scoring per gsk or pfizer solvent guides/product/Pfizer Inc
    Average 86 stars, based on 1 article reviews
    iv solvent hazard scoring per gsk or pfizer solvent guides - by Bioz Stars, 2026-06
    86/100 stars

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    Non-covalent DNMT1 <t>inhibitor</t> <t>GSK-3484862</t> induces DAXX-regulated DNMT1 SUMOylation. (A) Xenopus sperm nuclei were incubated in egg extracts supplemented with DMSO, GSK-3484862 or GSK-3484862 and ML-792. Isolated chromatin was analyzed by immunoblotting with indicated antibodies. (B) Immunoblotting results using indicated antibodies following DNMT1 immunoprecipitation of chromatin treated with or without GSK-3484862 for 60 min. The input results are shown in the lower panels. (C) Immunoblotting results of mock-depleted or DAXX-depleted egg extracts using indicated antibodies. (D) Xenopus sperm nuclei were incubated in mock-depleted or DAXX-depleted extracts treated with GSK-3484862 for 60 or 90 min. Isolated chromatin was analyzed by immunoblotting with indicated antibodies.
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    Non-covalent DNMT1 inhibitor GSK-3484862 induces DAXX-regulated DNMT1 SUMOylation. (A) Xenopus sperm nuclei were incubated in egg extracts supplemented with DMSO, GSK-3484862 or GSK-3484862 and ML-792. Isolated chromatin was analyzed by immunoblotting with indicated antibodies. (B) Immunoblotting results using indicated antibodies following DNMT1 immunoprecipitation of chromatin treated with or without GSK-3484862 for 60 min. The input results are shown in the lower panels. (C) Immunoblotting results of mock-depleted or DAXX-depleted egg extracts using indicated antibodies. (D) Xenopus sperm nuclei were incubated in mock-depleted or DAXX-depleted extracts treated with GSK-3484862 for 60 or 90 min. Isolated chromatin was analyzed by immunoblotting with indicated antibodies.

    Journal: Journal of Biochemistry

    Article Title: DAXX promotes SUMOylation of chromatin-trapped DNMT1

    doi: 10.1093/jb/mvag011

    Figure Lengend Snippet: Non-covalent DNMT1 inhibitor GSK-3484862 induces DAXX-regulated DNMT1 SUMOylation. (A) Xenopus sperm nuclei were incubated in egg extracts supplemented with DMSO, GSK-3484862 or GSK-3484862 and ML-792. Isolated chromatin was analyzed by immunoblotting with indicated antibodies. (B) Immunoblotting results using indicated antibodies following DNMT1 immunoprecipitation of chromatin treated with or without GSK-3484862 for 60 min. The input results are shown in the lower panels. (C) Immunoblotting results of mock-depleted or DAXX-depleted egg extracts using indicated antibodies. (D) Xenopus sperm nuclei were incubated in mock-depleted or DAXX-depleted extracts treated with GSK-3484862 for 60 or 90 min. Isolated chromatin was analyzed by immunoblotting with indicated antibodies.

    Article Snippet: For DNMT1 inhibition, egg extracts were incubated with 50 μM 5-aza-dCTP (Jena Bioscience) or with 100 μM GSK-3484862 (MedChemExpress).

    Techniques: Incubation, Isolation, Western Blot, Immunoprecipitation